Silicone injection websites

(clik aquí para la traducción española)

FDA warnings

U.S. Food and Drug Administration documents show links to autoimmune disorders, connective tissue disorders, genetic mutations, and cancer.

From http://www.fda.gov/cdrh/ost/rpt97/OST1997AR86.HTML

Autoimmune diseases have been reported in women with silicone breast implants. The presence of autoantibodies in some of the women, as well as studies in experimental animals, suggest that silicone may play a role in these adverse effects on the immune system.

Our earlier studies have shown that silicone gel/oil can promote autoantibody production against the connective tissue proteins, collagen, and can migrate from the implant site to other parts of the body.

Serum samples of 180 women have been analyzed for autoantibodies to collagen, a connective tissue protein. Patients included women with or without breast implants, with or without autoimmune symptoms, and from normal controls. Autoantibodies to collagen were detected in patients with connective tissue disease + silicone breast implants, with connective tissue disease without silicone breast implants, and with silicone breast implants without connective tissue disease. Autoantibodies to collagen were not detected in control sera from normal volunteers.

Published studies also have shown that animals with autoimmune disease produce antibodies against their own DNA. We have found anti-DNA antibodies in the serum of experimental animals injected with silicone gel/oil. Based on these results we will determine if women with breast implants also produce autoantibodies against DNA.

From http://www.fda.gov/opacom/backgrounders/collagen.html

Has liquid silicone been approved by FDA for injection?

No. FDA has not approved the marketing of liquid silicone for injection for any cosmetic purpose, including the treatment of facial defects or wrinkles, or enlarging the breasts. The adverse effects of liquid silicone injections have included movement of the silicone to other parts of the body, inflammation and discoloration of surrounding tissues, and the formation of granulomas (nodules of granulated, inflamed tissue).

Can FDA prohibit doctors from promoting the injection of liquid silicone, since its marketing has not been approved?

Yes. FDA prohibits manufacturers or doctors from marketing or promoting unapproved products such as liquid silicone. This means that a doctor cannot legally advertise or sell this material.

From http://vm.cfsan.fda.gov/~frf/forum97/97G14.htm

FDA on mutations and cancer (foreign body carcinogenesis):

After 12 months, fibrosarcoma in situ developed in 100% of rats implanted with either silicone or cellulose.

AEGIS warnings

The American Educational Gender Information Service (AEGIS) was an important early TG advocate in the field of health issues. They put out a series of articles, ads and pamphlets called Dangerous Curves Ahead, which remains an important overview of injectable silicone's dangers.

Advisories against the procedure:

http://www.gender.org/resources/curves.html

http://www.gender.org/resources/bad_news.html <-- highly recommended
http://www.gender.org/resources/malas_noticias.html (traduccion en español)

Other warnings and reports

American Society for Aesthetic Plastic Surgery advisory against the procedure:
http://surgery.org/news_releases/oct3001silicone.html

Side effects described by victim:
http://neuro-www.mgh.harvard.edu:16080/forum_2/SiliconeRelatedF/11.6.998.29AMREMOVALOFFAC.html

Granulomas:
http://ej.rsna.org/ej3/0112-99.fin/body/introduction-4.htm

Report on the silicone craze in Florida:
http://abcnews.go.com/sections/GMA/GoodMorningAmerica/GMA020128Silicone_lip_investigation.html
http://www.click10.com/mia/news/stories/news-56479220010329-130339.html
http://www.sptimes.com/News/041801/State/_It_s_food__drink_and.shtml

Silicone + laser skin resurfacing = flash fire:
http://archotol.ama-assn.org/issues/v127n4/abs/ooa00018.html

Risk overviews:
http://www.med.gazi.edu.tr/journal/1997_2_93_95.html
http://www.avitro.com/silsafe.htm

Risks and Complications of Liquid Silicone

http://www.yestheyrefake.net/liquid_silicone_risks.htm

Silicone Injection Web Resource

http://www.gotpummped.org [archive]

Cleopatra's needle: The history and legacy of silicone injections

http://leda.law.harvard.edu/leda/data/197/mwebb.html

Dr. Palmer

http://www.drfpalmer.com/blog/silicone-injections/

Queenz of Media

http://www.blogtalkradio.com/Queenz_OF_Media/2009/04/07/THE-DANGERS-OF-FREELY-INJECTED-SILICONE

NY Times

http://www.nytimes.com/2009/04/17/nyregion/17silicone.html